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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22733 | DL-AP5 | NMDAR | |
DL-AP5 is the racemic form of a selective N-methyl-D-aspartate (NMDA) receptor antagonist with anticonvulsant effects. | |||
T5S1131 | Ganoderic acid C6 | Others | |
1. Ganoderic acid C6 has antinociceptive activity. | |||
T6S0743 | Sesamoside | Others | |
Sesamoside has antinociceptive activity. | |||
TN2540 | 1-Hydroxybaccatin I | Others | |
1-Hydroxybaccatin I possesses significant antinociceptive activity against p- benzoquinone-induced abdominal contractions. | |||
T11516 | GV-196771A | NMDAR | |
GV-196771A A novel NMDA receptor glycine site antagonist with potent antinociceptive activity. | |||
T20225 | Dicentrine, (-)- | L-Dicentrine,NSC 251699,NSC251699,NSC-251699 | Others |
Dicentrine, (-)- (NSC-251699) is an aporphinic alkaloid found in several plant species, which showed significant antinociceptive activity in an acute model of visceral pain in mice. | |||
T5783 | Rosamultin | Antioxidant , HIV Protease | |
Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity. | |||
T21380 | Pravadoline | WIN 48098-6,WIN48098-6,WIN-48098-6 | Cannabinoid Receptor |
Pravadoline (WIN48098-6) is a cannabinoid receptor agonist. Pravadoline inhibited the PGs synthesis in mouse brain and displayed antinociceptive activity in rodents subjected to a variety of thermal, chemical, and mechan... | |||
T5S0662 | Gelsemine | Gelsemin | Antioxidant |
1. Gelsemine (Gelsemin) has antitumor activity. 2. Gelsemine has anti-oxidative activity. 3. Gelsemine has anti-hyperlipidemic activity. 4. Gelsemine has marked antinociception in inflammatory, neuropathic and bone cance... | |||
T8169 | Decursinol | Others | |
Decursinol is isolated from the roots of Angelica Gigas with an antinociceptive effect. It also has anti-tumor and anti-metastasis activity. | |||
T6S0627 | Mesaconitine | TNF | |
1. Mesaconitine has antiinflammatory activity. 2. Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system. | |||
TP1905 | BW-180C | DADLE | Opioid Receptor |
BW-180C (DADLE) is a prototypical δ-opioid receptor agonist that also displays activity at the μ-opioid receptor. Displays antinociceptive activity in vivo. | |||
T39284 | EST73502 HCl | Opioid Receptor | |
EST73502 is an agonist of μ-opioid receptor(Ki = 64 nM) agonist and an antagonist of σ1 receptor (Ki = 118 nM). EST73502 displays antinociceptive activity. | |||
T23076L | Nociceptin (1-7) acetate | Opioid Receptor | |
Nociceptin (1-7) acetate is a potent agonist of opioid receptor-like 1 (ORL1) receptor. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia and has antinociceptive activity. | |||
T23331 | SC 51089 | SC 51089 free base | Prostaglandin Receptor |
SC 51089 is a selective prostaglandin receptor PGE2 antagonist with selectivity for prostaglandin receptor subtypes and antinociceptive activity that improves motor deficits and rescues memory decline in the Huntington's... | |||
T3409 | Plantamajoside | Y0160,C10485 | Others |
Plantamajoside (Y0160) has anti-hepatotoxic, anti-inflammatory, antinociceptive activities, improving sexual function and antioxidant activity. | |||
TP1212 | N-Boc-Phe-Leu-Phe-Leu-Phe | Boc-FLFLF | Others |
N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) (Boc-FLFLF) is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin. Boc-Phe-Leu-Phe-Leu-Phe is used extensive... | |||
T3981 | Acacetin | 4'-Methoxyapigenin,5,7-Dihydroxy-4'-methoxyflavone,Linarigenin | Apoptosis , IAP , COX , Autophagy |
Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant activity in various research models. | |||
T4S1990 | Carvacrol | Karvakrol,O-Thymol,cymophenol | Apoptosis , Others , Gamma-secretase , Endogenous Metabolite , Antifungal |
1. Carvacrol (O-Thymol) presents anxiolytic effects. 2. 5-Isopropyl-2-methylphenol presents antinociceptive activity. 3. Carvacrol presents antidepressant effects, seems to be dependent on its interaction with the dopami... | |||
T10572 | BMT-124110 | AAK1 (AP2 associated kinase 1) | |
BMT-124110 is a selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibited BMP-2 induced protein kinase BIKE with IC50 of 17 nM. BMT-090605 inhibits cyclin G-associated kinase GAK with an... |